Tesofensine: The Next Evolution in Appetite Control

If you’ve been struggling to shed those last stubborn pounds or feel stuck in a frustrating weight loss plateau, it might be time to look beyond traditional approaches. Tesofensine, a cutting-edge appetite suppressant, is changing the game — and for good reason.

At Thiesen MD, we’re proud to offer Tesofensine as part of our advanced peptide therapy and metabolic optimization programs. Why? Because the science is compelling, the results are promising, and the benefits go far beyond the scale.

What Is Tesofensine?

Tesofensine is a novel compound originally developed for neurological conditions like Alzheimer’s and Parkinson’s disease. But during clinical trials, researchers made an unexpected discovery: participants consistently experienced significant weight loss. That’s because Tesofensine works directly on the brain’s appetite and reward centers, reducing cravings and boosting metabolic activity.

How Does Tesofensine Work?

Tesofensine inhibits the reuptake of three key neurotransmitters: dopamine, norepinephrine, and serotonin. This triple-action mechanism leads to: 

• Appetite suppression — Less hunger and fewer cravings 
• Enhanced energy levels — No stimulants required 
• Improved mood and focus — Supporting long-term lifestyle changes

By targeting these pathways, Tesofensine helps rewire the brain’s response to food — not just by curbing physical hunger, but by reducing the emotional and psychological drivers of overeating.

The Benefits of Tesofensine at Thiesen MD

Whether you’re just starting your journey or have hit a plateau, Tesofensine offers a new level of support: 

• Sustainable fat loss: Clinical trials have shown up to 10%+ body weight reduction over several months 
• No stimulant jitters: Unlike many weight loss medications, Tesofensine boosts energy without caffeine-like side effects 
• Better adherence: Fewer cravings mean you’re more likely to stick to healthy habits — effortlessly 
• Metabolic momentum: By elevating baseline energy levels, Tesofensine helps shift your body toward fat-burning mode

Why Tesofensine + Peptide Therapy Works

At Thiesen MD, we specialize in personalized peptide protocols that optimize hormone balance, cellular repair, and metabolism. Tesofensine fits seamlessly into this model, offering synergistic benefits when paired with peptides that support fat metabolism, insulin sensitivity, or thyroid function.

Is Tesofensine Right for You?

Tesofensine is ideal for those who are looking to break through weight loss resistance. It’s not a magic solution — but when combined with clinical support and a structured plan, it can be a powerful catalyst for transformation.

Let’s Talk: Your Journey Starts Here

Ready to learn if Tesofensine is right for you?

Contact the team at Thiesen MD today to schedule your personalized consu ltation and explore a smarter, science-backed path to lasting weight loss.

Call us at 401-307-2240, or fill out our form to get started today!